Education Background

NIH Ruth L. Kirschcstein NRSA Fellow
Doctorate of Philosophy, Environmental and Molecular Toxicology
Concentration: Molecular and Mechanistic Toxicology
Oregon State University, Corvallis, OR, Fall 2007 - Present

Master of Science, Environmental Science
School of Public and Environmental Affairs
Indiana University, Bloomington, IN, May 2005

Bachelor of Science, Chemistry
University of Virginia, Charlottesville, VA, May 2002

Contact Information

jill.franzosa@science.oregonstate.edu

Research Interest/Focus

Broadly, I am interested in the regulatory role of microRNAs in complex biological processes. My research focuses on understanding the functional role of microRNAs in molecular signaling pathways that control development and tissue regeneration. Our zebrafish model provides an excellent platform for investigating the effects of toxicant exposure on the expression and function of regulatory microRNAs during development. My research also exploits the regenerative capacity of zebrafish to understand the molecular events controlling epimorphic tissue regeneration.    

Peer Reviewed Publications

Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL. (2011). microRNAs control neurobehavioral development and function in zebrafish. PNAS Plus. Submitted.

Tal T.L., Franzosa J.A., Tanguay, R.L. (2009). The Molecular Signaling Networks that Choreograph Epimorphic Fin Regeneration in Zebrafish- A Mini-Review. Gerontology 56:231-240. PMID: 19923791.

Mathew LK, Sengupta S, Franzosa JA, Perry J, LaDu J, Andreasen EA, Tanguay RL. (2009). Comparative Expression Profiling Reveals an Essential Role for Raldh2 in Epimorphic Regeneration. JBC. 248(48): 33642-53. PMID: 19801676.

Franzosa JA, Osimitz TG, Maibach HI. (2009). Pyrethrins and pyrethrosin content in commercial allergen extracts. Dermatitis. 20(6): 338-40. PMID: 19958739.

Franzosa JA, Osimitz TG, Maibach HI. (2007). Cutaneous contact urticaria to pyrethrum – real?, common?, or not documented?: an evidence based approach. Cutan Ocul Toxicol. 25:287-308.

Osimitz TG, Franzosa JA, Maciver DR, Maibach HI. (2006). Pyrethrum allergic contact dermatitis in humans – real?, common?, or not documented?: an evidenced based approach. Cutan Ocul Toxicol. 25:287-308.

Yeager RL, Franzosa JA, Millsap DS, Angell-Yeager JL, Heise SS, Wakhungu P, Lim J, Whelan, HT, Eells JT, Henshel DS. (2006). Embryonic Growth and Hatching Implications of Developmental 670 nm Phototherapy – Dioxin Co-Exposure. Photomed Laser Surgery 24: 410-413.

Yeager RL, Franzosa JA, Millsap DS, Lim J, Heise SS, Wakhungu, P, Whelan, HT, Eells, JT, Henshel DS. (2006). Survivorship and Mortality Implications of Developmental 670 nm Phototherapy – Dioxin Co-Exposure. Photomed Laser Surgery 24:29-32.

Yeager RL, Franzosa JA, Millsap DS, Angell-Yeager JL, Heise SS, Wakhungu P, Lim J, Whelan HT, Eells JT, Henshel DS. (2005). Effects of 670 nm Phototherapy on Development. Photomed Laser Surgery 23:268-272.

Book Chapters

Simonich, M.T., Franzosa, J.A., and Tanguay, R.L. "In vivo approaches to predictive toxicology using zebrafish." New Horizons in Toxicity Prediction: A Comprehensive Overview of the Current Status and Application of Predictive Toxicology. (Submitted).

Honors/Awards

University Club of Portland.  Graduate Fellowship Award.  May 2011.

Department of Environmental and Molecular Toxicology.  Annual Research Day Symposium.  Corvallis, OR. Poster Presentation Award Winner (1st Place). January 2011.

National Institute of Health (NIA) Ruth L. Kirschstein NRSA Fellow (F31). September 2010 - Present

Society of Environmental Toxicology and Chemistry. Annual National Meeting, Portland, OR. Elsevier Best Platform Presentation in Toxicogenomics. Novemeber 2010.

Society of Environmental Toxicoloy and Chemistry. Annual National Meeting: Portland, Oregon. Graduate Student Travel Award: November 2010.

Society of Toxicology, Pacific Northwest Association of Toxicologist Conference, Poster Presentation Award (1st Place). October 2010.

Aquatic Animal Model for Human Disease. Annual Meeting, Corvallis, OR. Poster Presentation Award Winner. September 2010.

Society of Toxicology. Annual National Meeting: Salt Lake City, Utah. Molecular Biology Specialty Section Graduate Student Award (1st Place): March 2010.

Society of Toxicology. Annual National Meeting: Salt Lake City, Utah. Graduate Student Travel Award Recipient: March 2010.

American Association for the Advancement of Science (AAAS)/Science Program for Excellence in Science Nominee: 2010.

Department of Environmental and Molecular Toxicology. Annual Research Day Symposium: Corvallis, Oregon. Poster Presentation Award Winner: January 2010.

Society of Toxicology. Pacific Northwest Association of Toxicologist Conference. Platform Presentation Award (1st Place): September 2009.

National Institute of Health Pre-doctoral Training Grant Fellow: September 2007-September 2009.

Virginia Water Resources Research Center. Undergraduate Research Fellowship Recipient: May 2001.

Syracuse University. Chancellor's Scholar: 1998.